Maculopathy: New Treatments and Interventions


Maculopathy is the degeneration of the macula. The macula is the central part of the retina, the noblest part, the one that allows us to see the objects in front of us, to see details and distinguish colors.

The aging of the macula is associated with image distortion and the loss of the ability to distinguish faces and objects in front of us. Fortunately, however, this disease called maculopathy never leads to blindness and this is because peripheral vision is always preserved in some way. There are two main forms of maculopathy: there is wet maculopathy and dry maculopathy.

Wet Maculopathy

In wet maculopathy, abnormal blood vessels form under the macula which is thus damaged. In recent years there have been great innovations in the treatment of maculopathy. Today, thanks to intravitreal injections, which are injections that are given inside the eye, absolutely painless, it is possible to block wet maculopathy.

Dry Maculopathy

In dry maculopathy, however, there is progressive atrophy of the macula. As regards dry maculopathy, however, we still do not have a cure that can stop the disease, but there is some great news for these forms of maculopathy too. A diet rich in vitamins and antioxidants contained in colored fruit and vegetables (oranges, kiwis, strawberries, blueberries, berries, fish, apricots, carrots, pumpkin, spinach, etc.) and food supplements have proven to be somewhat effective in slow the progression of dry maculopathy. Fortunately, today new drugs and treatments for maculopathy are added to all this.

New Interventions Maculopathy

In both dry maculopathy and wet maculopathy there is the possibility, for example, of implanting intraocular lenses inside the eye. They allow you to enhance your peripheral vision. Normally, those suffering from maculopathy cannot see objects if they look straight ahead, but if they look to the side they can see the objects in front of them. These lenses allow objects that the person sees to be moved from the side by positioning them in front, and therefore allow these people to greatly improve their vision. There are various intraocular lenses for maculopathy, our experience is very successful with the EyeMax intraocular lens, there is the EyeMax mono for patients who need cataract surgery and the EyeMax add-on for patients who have already had cataract surgery.

New Maculopathy Treatments

Two important drugs for the treatment of maculopathy are in an advanced stage of testing and we hope to arrive by the end of the year: Brolucizumab for the treatment of wet maculopathy and GT005 from the English Gyroscope Therapeutics which is the first gene therapy to stop dry maculopathy. Recently available on the market, Luxturna is the first drug with proven efficacy in stopping hereditary maculopathy associated with gene mutation of the RPE65 gene. This is therefore a time of hope for those suffering from maculopathy. There are new drugs that are coming onto the market and which give very promising results, there are these intraocular lenses and there are a whole series of aids that technology has made available to us for those who are not candidates for either injections or lenses intraocular. So the advice is not to lose hope and contact a center specialized in the treatment of maculopathy because today the prognosis of maculopathy is much better than a few years ago. The experience of patients operated with the most innovative maculopathy interventions is available in the testimonials section with the hope that this can help give hope to those suffering from maculopathy.